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Proc Natl Acad Sci U S A, 1991
VarendiKAiravaaraMAnttilaJVoseSPlankenASaarmaMet al
Overall, compared with the large and growing amount of pre-clinical and mechanistic evidence highlighting the reward-modulating and thus potentially anti-addictive properties of GLP-1RAs, only a few studies have investigated thus far the potential use of these medications in clinical populations with alcohol- or other substance-use disorders
Easing side effects: One of the most common reasons that people microdose is a desire to avoid severe gastrointestinal side effects, like intense nausea, vomiting, or constipation
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